Compound | fu,plasma | fu,brain |
---|---|---|
Amprenavir | 0.0992 ± 0.0112 | 0.0687 ± 0.0131 |
Citalopram | 0.231 ± 0.013 | 0.0306 ± 0.0018 |
Digoxin | 0.284 ± 0.031 | 0.159 ± 0.004 |
Elacridar | 5.64E-05 ± 2.70E-05 | 1.50E-05a ± 7.15E-06a |
Imatinib | 0.0169 ± 0.0003 | 0.0441 ± 0.0017 |
Ko143 | 0.0293 ± 0.0051 | 0.00318 ± 0.00030 |
Loperamide | 0.040 ± 0.002 | 0.00572 ± 0.00064 |
Prazosin | 0.222 ± 0.008 | 0.107 ± 0.012 |
Quinidine | 0.274 ± 0.010 | 0.0508 ± 0.0128 |
Sulfasalazine | 0.00232 ± 0.00033 | 0.044 ± 0.002 |
Verapamil | 0.0582 ± 0.0034 | 0.0220 ± 0.0025 |
↵a Estimated from the mean ratio between fu,plasma and fu,brain for the other 10 compounds.