Pharmacokinetic parameters for tofacitinib and total radioactivity in human subjects (n=6)
All values correspond to mean (S.D.).
| Analyte | Tmax, | Cmax, | AUC0-last | AUC0-∞ | t1/2 |
|---|---|---|---|---|---|
| h | ng/ml or ng Eq/ml | ng*h/ml or ng Eq*h/ml | ng*h/ml or ng Eq*h/ml | h | |
| Tofacitinib | 1.1 (0.5) | 397 (62) | 1,670 (381) | 1,680 (380) | 3.2 (0.6) |
| Total radioactivity | 1.2 (0.4) | 611 (69) | 3,120 (621) | 3,440 (798) | 3.2 (0.5) |