TABLE 3

Percent of circulating GSK1322322 and metabolites after a single 1000-mg i.v. administration and a single 1200-mg oral administration of [¹⁴C]GSK1322322

Metabolite ID^{^a}	% Plasma Radioactivity^{^a}
	i.v.	Oral
M6	1.3	1.0
M9	10.7	14.6
GSK1322322	76.5	79.5^{^b}

M6, GSK2998310; M9, GSK2998314.
↵^a Structural identification based on cochromatography with standards of GSK1322322, GSK2998314, and GSK2998310.
↵^b M37, which coelutes with parent was determined to be <1% of GSK1322322 from mass spectrum response compared with synthetic standards in pooled human plasma; oral dose at 0.5 hour.