TABLE 1

LC-MS/MS conditions for compounds investigated and internal standards with details on mass transitions

No.	Compounds	Internal Standard	Electrospray Ionization	m/z	Collision Energy
					eV
1	Benazepril	Flecainide	Negative	423.1 > 173.9	−28
2	Cilazapril	Flecainide	Negative	416.1 > 166.9	−28
3	Quinapril	Flecainide	Negative	437.1 > 187.9	−30
4	Trandolapril	Flecainide	Positive	431.2 > 234.3	29
5	Perindopril	Flecainide	Positive	369.2 > 172.3	27
6	Ramipril	Flecainide	Negative	415.1 > 166	−34
7	Temocapril	Flecainide	Positive	477.2 > 190.2	45
8	Oseltamivir	Flecainide	Positive	313.2 > 165.8	27
9	Candesartan cilexetil	Flecainide	Negative	609.1 > 99	−68
10	Mycophenolate mofetil	Flecainide	Negative	432.2 > 244.8	−44
11	Olmesartan medoxomil	Flecainide	Negative	557.1 > 149	−62
	Flecainide	NA	Positive	415.1 > 398	33
		NA	Negative	413.2 > 269.9	−28