Brain trans-3′-hydroxycotinine (3HC) and norcotinine (NCOT) levels in EA and AD rats following s.c. nicotine
Data are presented as mean (S.D.).
| Time Point | Brain 3HC Level | Brain NCOT Level | ||
|---|---|---|---|---|
| EA | AD | EA | AD | |
| ng/g brain tissue | ||||
| 2 h | < LOQ | < LOQ | 4.3 (1.1) | 3.1 (0.9) |
| 4 h | 1.0 (0.7) | 1.4 (0.2) | 4.9 (1.9) | 5.1 (0.4) |
| 8 h | < LOQ | 1.2 (0.3) | 2.7 (0.1) | 3.5 (0.6) |