Determination of nicotine, nornicotine, cotinine, norcotinine, and trans-3′-hydroxycotinine in plasma from HIV-1–positive and HIV-negative smokers
| Patient | CD4 Count | Nicotine | Cotinine | Trans-3′-Hydroxycotinine | Nornicotine | Norcotinine |
|---|---|---|---|---|---|---|
| ng/ml | ||||||
| HIV-negative smokers | ||||||
| 1 | 1416 | 10.87 | 2.33 | 2.28 | 4.10 | 0.88 |
| 2 | 938 | 33.07 | 115.55 | 68.19 | 3.97 | 2.45 |
| 3 | 1488 | 14.85 | 123.38 | 24.33 | 2.15 | 1.61 |
| 4 | 1289 | 27.49 | 84.93 | 4.86 | 1.65 | 1.19 |
| 5 | 742 | 28.96 | 79.51 | 94.19 | 3.61 | 3.28 |
| 6 | 936 | 53.06 | 65.49 | 3.43 | 2.91 | 0.63 |
| 7 | 1438 | 61.59 | 119.04 | 71.65 | 1.91 | 3.87 |
| 8 | 1039 | 51.45 | 98.37 | 33.28 | 1.64 | 2.42 |
| 9 | 500 | 17.10 | 23.59 | 1.50 | 2.46 | 0.87 |
| 10 | 700 | 31.86 | 38.45 | 18.86 | 2.94 | 1.17 |
| 11 | 921 | 36.91 | 98.02 | 20.12 | 1.09 | 1.15 |
| Mean ± S.D. | 33.38 ± 16.41 | 77.15 ± 40.52 | 31.15 ± 32.38 | 2.58 ± 1.01 | 1.77 ± 1.08 | |
| HIV-1–positive smokers | ||||||
| 2 | 584 | 6.50 | 56.00 | 34.10 | 4.70 | 1.60 |
| 3 | 13 | 1.90 | 75.80 | 12.20 | 4.50 | 1.30 |
| 4 | 540 | 12.30 | 85.40 | 14.00 | 5.70 | 1.40 |
| 5 | 412 | 7.20 | 95.10 | 22.50 | 8.40 | 2.20 |
| Mean ± S.D. | 6.98 ± 4.26 | 78.08 ± 16.70 | 20.70 ± 10.00 | 5.83 ± 1.80 | 1.63 ± 0.40 | |