TABLE 4

Ratio of AUCOH-BUP to AUCBUP following a 1-mg/kg i.v. bolus dose of BUP to baboons during pregnancy and the postpartum period

P value from repeated-measures ANOVA: 0.959.

AUCOH-BUP/AUCBUP Ratio
MidpregnancyLate PregnancyPostpartum
Study animal
 10.720.92
 21.211.93
 30.430.260.54
 41.161.200.73
 50.620.631.00
Mean0.730.821.02
S.D.0.310.460.53