Demographics for hepatocyte donors used in the HepatoPac model to study protein interactions

DemographicsDonor 1Donor 2Donor 3aDonor 4b
Race/EthnicityCaucasianAfrican AmericanCaucasianNot provided
Cause of DeathIntracerebral bleed secondary to ICH/strokeCVAAnoxia secondary to CVANot provided
Medical HistoryLupusDiabetes, hypertension, kidney disease, insulinDiabetes and hypertension, 3 years, medicine compliantNot provided
Social HistoryNo alcohol, tobacco, or drug useNo alcohol, tobacco, or drug useNonsmoker, social drinkerNot provided
  • CVA, cerebrovascular accident; ICH, intracerebral hemorrhage.

  • a This donor was determined through genotyping analysis to be organic anion-transporting polypeptide (OATP) wild type and CYP3A5 *3*3

  • (Ramsden et al., 2014a).

  • b Donor ID “RTM” from the manufacturer.