Rat Age | ||||||
---|---|---|---|---|---|---|
<1 Week | 1 Week | 2 Weeks | 3 Weeks | 4 Weeks | 8 Weeks | |
Km (μM) | 25.6 ± 1.4 | 22.5 ± 12.8 | 21.1 ± 5.4 | 12.0 ± 0.8 | 28.0 ± 10.6 | 19.3 ± 5.7 |
Vmax [pmol/(min × million cells)] | 1024.5 ± 319.0*** | 2032.5 ± 828.0* | 1038.2 ± 431.0*** | 1231.7 ± 272.5*** | 3494.0 ± 514.3 | 3887.0 ± 639.3 |
CL (Vmax/Km) [μl/(min × million cells)] | 42.0 ± 15.4* | 95.4 ± 7.7 | 49.3 ± 16.1* | 101.9 ± 16.6 | 138.8 ± 56.4 | 220.9 ± 103.1 |
Kd [μl/(min × million cells)] | 0.2 ± 0.2** | 0.7 ± 0.9** | 2.7 ± 1.4** | 3.2 ± 2.8** | 9.1 ± 4.6 | 12.8 ± 2.5 |