Cmaxa | [I]/Kis | Reference(s) | |
---|---|---|---|
μM | |||
Milk thistle constituents | |||
Silybin A | 0.6–0.8 | 0.1 | Zhu et al. (2013), Brantley et al. (2014b) |
Silybin B | 0.3–0.4 | 0.01 | Zhu et al. (2013), Brantley et al. (2014b) |
Isosilybin A | 0.02–0.07 | 0.005–0.01 | Wen et al. (2008), Zhu et al. (2013) |
Isosilybin B | 0.02–0.2 | 0.007–0.07 | Wen et al. (2008), Zhu et al. (2013) |
Silydianin | 0.01 | 0.0003 | Zhu et al. (2013) |
Silychristin | 0.02 | 0.003 | Zhu et al. (2013) |
Taxifolin | 0.02 | 0.003 | Zhu et al. (2013) |
Green tea constituents | |||
EGCG | 0.4–1 | 1–3 | Chow et al. (2001), Misaka et al. (2014) |
ECG | 0.1 | 0.3 | Misaka et al. (2014) |
Other dietary constituents | |||
Quercetin | 0.03 | 0.03 | Wang and Morris (2005) |
Resveratrol | 0.3–2 | 0.06–0.4 | Boocock et al. (2007) |
↵a Cmax values were limited to studies of healthy volunteers, from whose plasma the parent constituent was measured directly (i.e., independently from any of the metabolites). Suitable data were not available for six constituents.