Relative abundance (percentage of total administered dose) of urinary and fecal metabolites of PF-04991532 in rats and dogs after oral administration of [14C]PF-04991532
| Metabolites | Rat | Dog | ||||
|---|---|---|---|---|---|---|
| Urine | Feces | Total | Urine | Feces | Total | |
| PF-04991532 | 10.9 | 66.6 | 77.5 | 11.5 | 38.7 | 50.2 |
| M1 | 0.1 | 2.2 | 2.3 | 0.5 | 1.4 | 1.9 |
| M2a/M2b | 0.4 | 8.2 | 8.6 | |||
| M3 | 0.1 | 0.1 | ||||