Theoretical human BChE inhibition by BMB with and without the contribution of MONO
BChE maximal inhibition % (time).
| Compound | 30°C | 37°C | ||
|---|---|---|---|---|
| With MONO Contribution | Without MONO Contribution | With MONO Contribution | Without MONO Contribution | |
| rac-BMB | 54% (40 min) | 40% (19 min) | 53% (20 min) | 41% (12 min) |
| R-BMB | 61% (40 min) | 46% (12 min) | 59% (19 min) | 45% (4 min) |
| S-BMB | 45% (40 min) | 40% (29 min) | 46% (19 min) | 40% (12 min) |
| Isoactivity point | >180 min | 38 min | ∼120 min | 19 min |