Summary of metabolites of EPZ011652 observed in rats
| Metabolite | Mass Shift (Da) | m/z | Product Ions (m/z) | Rat Plasma (0–4 h) | Rat Bile (0–4 h) |
|---|---|---|---|---|---|
| Parent | 0 | 289.201 | 215.120, 173.069, 146.059, 75.091 | √ | √ |
| M1 | +42 | 331.213 | 215.120, 173.069, 117.103 | √ | √ |
| M2 | +58 | 347.208 | 231.121, 173.069, 117.103 | √ | |
| M3 | +80 | 369.123 | 253.027, 173.069, 117.103 | √ | √ |
| M4 | +66 | 355.108 | 253.027, 173.069, 103.094 | √ |