TABLE 1

Pharmacokinetic parameters obtained after administration of 100 nM hydrocortisone to a coculture of human hepatocytes and Kupffer cells in the human liver bioreactor

Symbol	Characteristic	Value	Unit
t_1/2	Elimination half-life	23	h
k_el	Elimination rate constant	0.03	h⁻¹
V_d	Volume of distribution	2.2	ml
CL	Clearance	6.6 × 10⁻⁵	l⋅h⁻¹
AUC	Area under the curve	1.03