TABLE 5

Results of analyzing CYP3A enzyme recovery data upon removal of 10,000 or 1000 pg/ml of IL6 with eqs. 11 and 12

Parameter	Estimate	SE	95% CI	R²	AIC	Removal of Treatment (IL6)
	h⁻¹	CV %
k_deg (assuming k_deg,RNA = 0.0282 h⁻¹)	0.0335	7.76%	[0.0268, 0.00402]	0.996	−31.5	1000 pg/ml
k_deg (assuming k_deg,RNA = 0.0282 h⁻¹)	0.0231	11.7%	[ 0.0161, 0.0300]	0.992	−24.2	10,000 pg/ml
k_deg_,_RNA (assuming k_deg = 0.0316 h⁻¹)	0.0296	6.50%	[ 0.0247, 0.0346]	0.996	−31.5	1000 pg/ml
k_deg_,_RNA (assuming k_deg = 0.0316 h⁻¹)	0.0213	10.7%	[0.0154, 0.0271]	0.992	−24.1	10,000 pg/ml

AIC, Akaike information criterion; CI, confidence interval; CV, coefficient of variation; R2, coefficient of determination; SE, standard error.