TABLE 2

Summary of P450 modulations

Model	P450 Enzyme	Prehypertrophy Phase	Hypertrophy Phase
		72 h
In vivo	CYP2B1	↔	↑
	CYP2C23	↓	↓
	CYP2J3	↓	↑
	CYP4F4	↑	↑
		6 h
In vitro	CYP1A2	↔	↓
	CYP2B6	↓	↓
	CYP2C8	↓	↓
	CYP2C19	↔	↓
	CYP2J2	↓	↓ → ↔
	CYP4F2	↓	↓