TABLE 2

Apparent permeability coefficients (Papp) of C7G and calycosin at different concentrations on a Caco-2 cell model

ConcentrationC7GCalycosin
Papp A to BPapp B to AEfflux ratioPapp A to BPapp B to AEfflux ratio
μM10-7cm/s10−7cm/s
12.515.2 ± 2.5713.2 ± 1.430.86307.0 ± 3.97407.8 ± 10.51.33
2511.0 ± 3.818.54 ± 0.610.78263.7 ± 6.23377.9 ± 16.41.43
508.28 ± 2.918.16 ± 1.050.99291.3 ± 9.32338.1 ± 24.31.16
10013.1 ± 2.098.14 ± 1.560.62313.2 ± 3.15407.8 ± 9.521.30