TABLE 2

Kinetic parameters of OT conversion by CYP11B1, CYP11B2, and CYP11A1 determined as shown in Fig. 5

P450 EnzymeKMkcatkcat/KM
µMmin−1min−1 mM−1
CYP11B133 ± 925 ± 2741
CYP11B210 ± 234 ± 23338
CYP11A1136 ± 216 ± 0.446