TABLE 2

Pharmacokinetic parameters for the conversion of hydrocortisone to cortisone

Central Volume of DistributionPeripheral Volume of DistributionTotal Volume of Distribution Intercom-partmental ClearanceElimination ClearanceFraction of Dose EliminatedElimination Half-Life
Hydrocortisoneml 3.03ml 0.86ml 3.89ml/h 0.93ml/h 0.041h 67.3
CortisoneN/AN/A4.0N/A0.29N/AN/A
  • N/A, not applicable.