Transport Parameter | Value |
---|---|
Km (μM) | 4.0 ± 0.5 |
Vmax (pmol/min per million cells) | 399 ± 22 |
Clint,up,act (μl/min per million cells) | 100 ± 14 |
Clint,up,pass (μl/min per million cells) | 134 ± 4 |
Clint,eff (μl/min per million cells) | 420 ± 99a |
% Active uptake at Cmax,u | 37% |
% Passive uptake at Cmax,u | 63% |
↵a Clint,eff was determined from uptake and elimination rates as reported in Supplemental Equation 1 and Supplemental Table 1.