TABLE 1

Multiple reaction monitoring (MRM) transitions of the used peptides and the corresponding internal standards (AQUA)

NameLabeledPeptide SequenceaMolecular WeightQ1Q3-1Q3-2Q3-3Q3-4
ABCB1UnlabeledNTTGALTTR934.0467.7719.4216.1618.4
AQUANTTGALTTR950.0471.2726.5
ABCC2UnlabeledVLGPNGLLK910.1455.8698.5185.3213.3
AQUAVLGPNGLLK926.1459.2705.4
ABCC3UnlabeledALVITNSVK944.1472.8760.4661.4548.4
AQUAALVITNSVK950.1475.8766.5
ABCG2UnlabeledSSLLDVLAAR1.044.2522.8644.3757.5529.4
AQUASSLLDVLAAR1.060.2526.3651.3
BSEPUnlabeledSTALQLIQR1.029.2515.3657.4841.6529.4
AQUASTALQLIQR1.045.2518.8664.3
GLUT1UnlabeledVTILELFR990.2495.8790.5677.4201.2
AQUAVTILELFR1.000.2500.8800.5
MCT1UnlabeledSITVFFK841.0421.2173.2641.3201.1
AQUASITVFFK851.0426.2651.3
OCTN2UnlabeledWLISQGR859.0430.2560.3272.2300.2
AQUAWLISQGR875.0433.7567.3
OATP1B1UnlabeledLNTVGIAK815.0408.2399.4588.3228.2702.3
AQUALNTVGIAK831.0411.7402.9
OATP2B1UnlabeledSSISTVEK849.9425.7563.3676.3175.1
AQUASSISTVEK855.9428.7569.3
  • a AQUA: Amino acid presented in bold is labeled with 13C and 15N.