Regression coefficients for gene expression and BPA levels in human fetal livers
Regression coefficients (β) were calculated from simple linear regression analysis for each gene and BPA species (n = 49).
| Gene | BPA Species | |||||
|---|---|---|---|---|---|---|
| Total | Conjugated | Free | ||||
| β | P Value | β | P Value | β | P Value | |
| MRP1 | 1.45 × 10−3 | 0.666 | 1.13 × 10−2 | <0.001* | 4.36 × 10−4 | 0.728 |
| MRP2 | 3.79 × 10−4 | 0.815 | 5.54 × 10−3 | 0.038** | −3.14 × 10−4 | 0.779 |
| MRP3 | 8.82 × 10−4 | 0.350 | 7.12 × 10−3 | 0.013** | 2.26 × 10−4 | 0.851 |
| MRP4 | 1.19 × 10−3 | 0.185 | 4.79 × 10−3 | 0.085 | 1.11 × 10−3 | 0.332 |
| MDR1 | 5.16 × 10−4 | 0.677 | 3.37 × 10−3 | 0.380 | 2.62 × 10−4 | 0.868 |
| BCRP | 1.03 × 10−3 | 0.288 | 4.45 × 10−3 | 0.138 | 9.08 × 10−4 | 0.462 |
| NRF2 | 1.82 × 10−3 | 0.057 | 1.04 × 10−2 | <0.001* | 1.19 × 10−3 | 0.334 |
| NQO1 | 1.66 × 10−3 | 0.124 | 1.27 × 10−2 | <0.001* | 1.19 × 10−3 | 0.334 |
* P < 0.001; **P < 0.05.