TABLE 5

Fetal and postnatal H3Ac/H3K27me3 ratios within the CYP3A4 XREM binding region

Tissue SourceH3Ac/H3K27me3 Ratio
XREM AmpliconRegion
12345
Fetal0.160.090.091.030.610.11
Postnatal0.440.060.054.280.500.09