Percentages of radioactivity for dasabuvir and corresponding metabolites in human plasma (N = 4) after administration of a single 400-mg oral dose of [14C]dasabuvir
Data are presented as means ± S.D.
| Metabolite | Percentage of Radioactivity in Plasma |
|---|---|
| Dasabuvir | 58.1 ± 4.6 |
| M1 | 21.4 ± 2.4 |
| M2 | 6.6 ± 2.4 |
| M3 | 4.4 ± 3.0 |
| M4 | 1.7 ± 1.3 |
| M5 | 1.7 ± 1.7 |
| M6 | 2.3 ± 2.0 |
| U1 | 4.7 ± 1.1 |