Compound | Ombitasvir | M2 | M9 | M3 | M6 | M5 | Uf1-3a | Mu1-5b |
---|---|---|---|---|---|---|---|---|
Feces (0–192 h)c | 87.8 | 0.2 | 0.7 | 0.6 | 0.2 | 0.2 | 0.6 | — |
Urined | 0.03 | — | — | — | — | — | — | 0.57 |
Subtotal | 87.83 | 0.2 | 0.7 | 0.6 | 0.2 | 0.2 | 0.6 | 0.57 |
Mu, unknown metabolites in urine; Uf, unknown metabolites in feces.
↵a Uf1-3 is the combined radioactivity dose recovery for Uf1, Uf2, and Uf3.
↵b Mu1-5 is the combined radioactivity dose recovery for Mu1, Mu2, Mu3, Mu4, and Mu5.
↵c Sum of radioactivity dose recovery from 0–192-hour pooled feces.
↵d Sum of radioactivity dose recovery from 12–24-, 48–72-, and 168–192-hour pooled urines.