Predicted effect of four nsSNPs
| Parameters | Gly376Ser | Ala181Thr | Val432Ile | Pro488Leu |
|---|---|---|---|---|
| PolyPhen-2 | ||||
| Score | 0.936 | 0.011 | 0.004 | 0.042 |
| Function | Possibly damaging | Benign | Benign | Benign |
| MutationTaster | ||||
| Function | Probably harmless | Probably harmless | Probably harmless | Probably harmless |
| SIFT | ||||
| Score | 0.05 | 0.07 | 1 | 0 |
| Function | Damaging | Tolerated | Tolerated | Damaging |