KI and kinact values for clomethiazole (CMZ) and human liver microsomal and rCYP2E1a
| Enzyme Source | KI Value | kinact Value | kinact/KI Ratio |
|---|---|---|---|
| Pooled human liver microsomes | µM | min−1 | µl min−1 nmol−1 |
| 40 ± 7.0 | 0.35 ± 0.022 | 8.8 | |
| CYP2E1 Supersomes | 41 ± 1.7 | 0.32 ± 0.048 | 7.8 |
↵a Each value represents the mean ± range of two independent experiments.