TABLE 1 

Proteins and peptides quantified in the kidney tissue

ProteinTissue LocalizationaDetected Peptide
NephrinPodoELVLVTGPSDNQAK
Podocalyxin-likePodoLGDQGPPEEAEDR
PodocinPodoLPAGLQHSLAVEAEAQR and SLTEILLER
CD34Mes, Glom endoLGILDFTEQDVASHQSYSQK and SWSPTGER
Aldolase BPTELSEIAQSIVANGK
Arginosuccinate synthase 1PTAPNTPDILEIEFK
Cathepsin HPTVNHAVLAVGYGEK
Dicarbonyl/L-xylulose reductasePTTQADLDSLVR
Dipeptidase 1PTVASLIGVEGGHSIDSSLGVLR
OAT1PTTSLAVLGK
OAT3PTTVLAVFGK
OCT2PTSPGVAELSLR and LNPSFLDLVR
SERPINA1PTDTEEEDFHVDQVTTVK
SGLT2PTLEDISEDPSWAR
P-gp (MDR1)PT, MesNTTGALTTR
Tamm-Horsfall proteinTALDWVSVVTPAR
Golgi membrane protein 1DTINLLDQR
Aquaporin 2CDQSVELHSPQSLPR and SLAPAVVTGK
Carbonic anhydrase 2DCT, CDYDPSLKPLSVSYDQATSLR
Tight junction protein 1 (ZO1)Podo, TAL, DCT, CDDNPHFQSGETSIVISDVLK
PlakoglobinPT, TAL, DCT, CDLLNQPNQWPLVK
Claudin 5EndoEFYDPSVPVSQK and VYDSVLALSTEVQAAR
Intercellular adhesion molecule 2EndoILLDEQAQWK
  • Podo, glomerular podocytes; Mes, glomerular mesangial cells; PT, proximal tubule; TAL, thick ascending limb of the loop of Henle; DCT, distal convoluted tubule; CD, collecting duct; Endo, endothelial cells

  • a Ernest et al., 1997; Kwon et al., 1998; Miyanaka et al., 1998; Motohashi et al., 2002; Reyes et al., 2002; Higgins et al., 2004; Kuusniemi et al., 2004; Aires et al., 2013; Motohashi et al., 2013; Fujinaka et al., 2014.