TABLE 2

Age-dependent protein abundance (pmol/mg total protein, mean ± SD) of CES1, CES2 and total CES1 plus CES2 in human liver microsomes and cytosols

Age CategoryCES1CES2CES1 + CES2
MicrosomalCytosolicMicrosomalMicrosomal
Neonatal315.2 ± 241.1184.2 ± 150.959.8 ± 26.2374.9 ± 266.4
Infancy722.2 ± 535.9255.7 ± 184.0134.3 ± 91.4856.5 ± 614.2
Early childhood1262.1 ± 434.3288.0 ± 168.4154.4 ± 71.41416.5 ± 488.8
Middle childhood1216.5 ± 448.4351.5 ± 265.6155.6 ± 60.81372.1 ± 498.7
Adolescence1261.5 ± 469.5495.5 ± 241.6165.2 ± 72.01426.7 ± 524.4
Adulthood1664.4 ± 781.7556.5 ± 311.1174.1 ± 105.71829.1 ± 856.2