TABLE 1

Plasma bile acid levels in rats receiving oral administration of 100 mg/kg/day NIM or 0.5% CMC-Na for 5 days

Blood samples were collected at 24 hours after the last dose. Data are reported as the mean ± S.D. (n = 6).

No.	Bile acid	Control	NIM	Fold
		ng/ml
1	CA^{^a}	2530 ± 1050	7233 ± 2845	2.86
2	DCA^{^a}	290 ± 107	779 ± 424	2.68
3	CDCA^{^a}	928 ± 221	3593 ± 1767	3.87
4	UDCA^{^a}	1143 ± 413	3433 ± 2082	3.00
5	LCA	47 ± 17	76 ± 48	1.62
6	GCA	376 ± 84	388 ± 183	1.03
7	GDCA	166 ± 25	148 ± 37	0.89
8	GCDCA	140 ± 54	195 ± 44	1.39
9	GUDCA	113 ± 23	157 ± 45	1.39
10	TCA	55 ± 3	41 ± 12	0.74
11	TCDCA	59 ± 11	46 ± 15	0.77