TABLE 6

fT,homogenate in human liver homogenate

Values are shown as the mean ± S.D. (n = 3).

DrugfT,homogenate
37°COn Ice37°C/On Ice Ratio
Diazepam0.0259 ± 0.00180.0242 ± 0.00161.07 ± 0.10
Pitavastatin0.0301 ± 0.00170.0344 ± 0.00180.875 ± 0.067
Rosuvastatin0.237 ± 0.0370.206 ± 0.0251.15 ± 0.23
Pravastatin0.183 ± 0.0220.167 ± 0.0201.10 ± 0.19