TABLE 1

Transporter Certified Cryopreserved Hepatocytes

Hepatocyte LotSexExperimentFigure
HUM4059Female24-hour cytotoxicity assessmentFig. 1A
HUM4075BMale72-hour cytotoxicity assessmentFig. 1B
HUM4059FemaleCYP3A4/5 inhibition evaluationFig. 2
HUM4109FemaleCYP3A4 mRNA induction assessmentFig. 3
HUM4122CMaleIntracellular concentration evaluationFig. 4
HUM4122CMaleMDZ intrinsic clearance studiesFigs. 5 and 6