TABLE 1

Mass spectrometer parameters for AZD6738, AZ8982 (sulfoxide), and AZ0002 (sulfone)

AnalyteAZD6738AZ8982AZ0002
MRM m/z (Parent → Daughter)413.1352 > 334.2479397.9886 > 335.2584414.1475 > 264.2618
Dwell (s)0.0560.0560.056
Cone Voltage (V)401010
Collision Energy (V)282240
  • MRM, multiple reaction monitoring.