Viscera indices in CYP2C11-null and WT rats at 60 days old
All values are shown as the mean ± S.D., n = 6. *P < 0.05 compared with that of WT rats.
| Viscera Indicesa | Male | Female | ||
|---|---|---|---|---|
| WT | Null | WT | Null | |
| Body weight (g) | 254 ± 7.46 | 234.18 + 27.70 | 148.32 ± 4.17 | 162.97 + 21.68 |
| Liver (%) | 6.47 ± 0.60 | 5.92 ± 2.07 | 5.16 ± 0.29 | 5.98 ± 2.72 |
| Spleen (%) | 0.40 ± 0.05 | 0.29 ± 0.03 | 0.25 ± 0.03 | 0.25 ± 0.03 |
| Lungs (%) | 0.74 ± 0.11 | 0.68 ± 0.08 | 0.79 ± 0.07 | 0.64 ± 0.15 |
| Kidney (%) | 1.24 ± 0.14 | 1.08 ± 0.17 | 0.97 ± 0.05 | 0.95 ± 0.17 |
| Testis (%) | 1.00 ± 0.19 | 1.25 ± 0.12 | ||
| Brain (%) | 0.89 ± 0.04 | 0.61 ± 0.07* | 0.87 ± 0.05 | 0.76 ± 0.13 |
↵a Viscera index = tissue weight (g)/rat body weight (g) × 100%.