TABLE 3 

Recovery of verinurad and metabolites in excreta as a percentage of verinurad dose

PathwayTime Period (h)% of Dose
M1M4M8OthersaVerinuradTotal
Urineb0–4829.20.3332.50.361.1763.6c
Fecesb0–120NDNDND0.6729.930.6
Total excretad0–12029.20.3332.51.0331.194.2
  • ND, Not detectable.

  • a Others: including unidentified minor metabolites.

  • b Urine collection up to 48 hours; and feces collection up to 120 hours.

  • c Urine collection from 0 to 120 hours recovered 64.5% of dose.

  • d The recovery of total radioactivity from 0 to 144 hours interval was 97.1%.