TABLE 5

Univariate associations between SNPs and BCRP protein expression

SNPa,bRegression Parameter Estimate for Additive Effect on BCRP Protein ExpressionS.E. of Parameter Estimate for Additive Effect on BCRP Protein Expressiont-Statistic for SNP Effect on BCRP Protein ExpressionP Value for SNP Effect on BCRP Protein ExpressionBonferroni-Adjusted P Value for SNP Effect on BCRP Protein Expression
C46847T0.02470.01691.460.1491.000
G46932C−0.00230.0256−0.090.9281.000
G59582A0.02130.01781.200.2351.000
A61562C0.00970.03260.300.7671.000
C61785T0.01200.02150.560.5781.000
C72144T−0.02790.0148−1.880.0651.000
T73809C−0.02100.0147−1.420.1591.000
C78551T0.02270.02271.2200.2271.000
A92873G0.01420.01580.900.3731.000
A92894C0.02070.01510.1370.1751.000
T93490C0.01020.01800.570.5741.000
C93624A−0.02940.0154−1.910.0601.000
G94112A0.01040.2250.460.6461.000
A96567G0.00080.02740.030.9761.000
C421Ac−0.06660.0195−3.420.0010.018
T141300C0.00970.01840.530.5981.000
A141618G−0.02270.0147−1.540.1271.000
  • a AC084732 (first nucleotide of gene = 1).

  • b SNPS G34A, C369T, and C376T were removed from analysis due to small sample size.

  • c Starting at translational start site (+1) and excluding nucleotides in the noncoding region.