TABLE 3

ASP+ accumulation is decreased in ciPTEC-OAT1 and ciPTEC-OAT3

Km (represented in micromolar concentration) and Vmax values (represented in min−1) calculated from Michaelis-Menten fitted ASP+ accumulation assays in ciPTEC-parent, ciPTEC-OAT1, and ciPTEC-OAT3 (mean ± S.E.M., n = 3, *P < 0.05; **P < 0.01; ***P < 0.001; compared with ciPTEC-parent by one-way analysis of variance).

KmVmax
ciPTEC-parent2.3 ± 0.323.5 ± 0.1
ciPTEC-OAT14.7 ± 0.4*13.1 ± 0.3***
ciPTEC-OAT36.2 ± 0.3***21.6 ± 0.6**