TABLE 4

Univariate associations between SNPs and BCRP mRNA expression

SNPa,bRegression Parameter Estimate for Additive Effect on BCRP mRNA ExpressionS.E. of Parameter Estimate for Additive Effect on BCRP mRNA Expressiont-Statistic for SNP Effect on BCRP mRNA ExpressionP Value for SNP Effect on BCRP mRNA ExpressionBonferroni-Adjusted P Value for SNP Effect on BCRP mRNA Expression
C46847T−0.00820.0082−1.000.3181.000
G46932C0.00140.01290.110.9121.000
G59582A0.00160.00940.170.8641.000
A61562C−0.02940.0155−1.900.0601.000
C61785T0.00190.01040.180.8571.000
C72144T0.00400.00740.550.5861.000
T73809C0.00600.00740.820.4151.000
C78551T0.00660.01090.610.5431.000
A92873G0.00310.00790.390.6951.000
A92894C−0.00620.0074−0.840.4011.000
T93490C0.00350.00810.430.6651.000
C93624A0.00910.00751.220.2251.000
G94112A−0.01470.0109−1.360.1771.000
A96567G−0.00720.0127−0.570.5701.000
C421Ac0.00290.01090.260.7941.000
T141300C−0.00130.0085−0.150.8821.000
A141618G−0.00090.0074−0.120.9031.000
  • a AC084732 (first nucleotide of gene = 1).

  • b SNPS G34A, C369T, and C376T were removed from analysis due to small sample size.

  • c Starting at translational start site (+1) and excluding nucleotides in the noncoding region.