Peak Number in Fig. 2 | HPLC Rt (min) | MRM Transition | CYP2C19 | CYP2D6 | CYP3A |
---|---|---|---|---|---|
min | |||||
Peak 3 | 1.18 | 549 → 232 | 4.3% | ||
Peak 5 | 1.46 | 373 → 232 | 0.47% | 0.83% | |
Peak 6 | 1.53 | 373 → 174 | 0.06% | 0.90% | |
Peak 7 | 1.66 | 389 → 160 | 4.5% | 10% | |
Peak 8 | 1.69 | 549 → 232 | 3.3% | ||
Peak 9 | 1.70 | 373 → 232 | 0.69% | ||
Peak 10 | 1.91 | 369 → 228 | 0.85% | 1.1% | |
Peak 11 | 1.91 | 389 → 248 | 0.80% | 0.90% | |
Peak 13 | 2.0 | 373 → 232 | 3.4% | ||
Peak 14 | 2.06 | 288 → 147.1 | 5.5% | ||
Peak 15 | H2.04 | 346 → 160.1 | 2.4% | ||
SAM-760 fraction metabolized (fm) | N/A | N/A | 6.3% | 0.47% | 33% |
N/A, not applicable.