Peptide sequences of GSTZ1C with post-translational modification sites
Bold, underlined amino acids were modified; unknown indicates sequence not covered.
| Sequence | Modification | Cytosolic GSTZ1C | Mitochondrial GSTZ1C | hGSTZ1C |
|---|---|---|---|---|
| (M)QAGKPILYSYFR(S) | Gln > Pyro-Glu | Unknown | Unknown | Y |
| (K)DFQALNPMK(Q) | Gln > Pyro-Glua | N | N | Y |
| (K)DFQALNPMK(Q) | Oxidation | Y | Y | Y |
| (K)QVPTLKIDGITIHQSLAIIEYLEETRPTPR(L) | Gln > Pyro-Glua | N | N | Y |
| (R)MISDLIAGGIQPLQNLSVLK(Q) | Oxidation | Y | Y | Y |
| (R)MISDLIAGGIQPLQNLSVLK(Q) | Deamidated | N | N | Y |
| (R)FKVDLTPYPTISSINKR | Phosphorylation | N | N | Y |
| (R)FKVDLTPYPTISSINKR | Deamidated | Y | N | Y |
| (R)QPDTPTELRA | Gln > Pyro-Glua | Y | Y | Y |
N, modification not found; Pyro-Glu, pyroglutamate; Y, modification found.
↵a Pyroglutamate is formed from cyclization of N-terminal glutamine.