TABLE 2

 Characteristics of the activities at the isoform, microsomal, liver tissue, and liver levels in human liver microsomes (n = 82)

VariablesMedianRange95% PI50% PI
V2B7 (pmol/min per picomole of 2B7)Range7.52–243.7–236.1–11
Ratio12.06.21.8
CL2B7 (μl/min per picomole of 2B7)Range0.080.02–0.310.03–0.230.06–0.12
Ratio15.57.72.0
VM (nmol/min per milligram of protein)Range0.910.44–2.10.5–1.90.8–1.1
Ratio4.83.81.4
Km (μM)Range9443–18247–16581–108
Ratio4.23.51.3
CLM (μl/min per milligram of protein)Range10.44.6–24.25–238.7–13
Ratio5.34.61.5
VLT (nmol/min per gram of liver)Range376.6–1099.6–10024–57
Ratio16.510.42.4
CLLT (ml/min per gram of liver)Range0.410.072–1.50.12–1.30.23–0.64
Ratio20.810.82.8
VL (μmol/min per kilogram)Range0.760.16–2.30.22–2.20.5–1.2
Ratio14.410.02.4
CLL (ml/min per kilogram)Range8.61.8–322.7–314.9–14
Ratio17.811.52.9
  • Ratio, the ratio of the maximum to the minimum.