TABLE 2

M1 levels in kidney transplant patients’ stool samples

PatientAgeGenderPost-Transplant DayTacrolimus Oral DoseaFecal AbundanceBaseline Level in Stool SamplesM1 Production upon Tacrolimus Incubation
F. prausnitziiClostridialesTacrolimusM1
yrmg/day%%ng/mg stoolng/mg stoolng/mg stool
145Female31946860.880.385.1
256Male1833989BQLbBQLb3.5
361Male20532710.63BQLb4.5
459Female12627760.710.122.9
550Male321026790.370.416.4
652Female286ND150.29BQLb3.5
757Male153ND440.85BQLb4.1
871Male184ND95BQLb0.607.1
925Male274ND740.49BQLb12.6
1052Male326ND950.14BQLb11.0
  • BQL, below the quantification limit; ND, not detected.

  • a At the time of stool collection.

  • b Below the quantification limit (i.e., 0.1 ng/mg stool).