TABLE 1

NC- and α-NF–induced inhibition of EROD activity of CYP1A1, CYP1B1, and CYP1A2

Data represent the mean ± S.D. (n = 3).

InhibitorIC50
CYP1A1CYP1B1CYP1A2
μMμMμM
NC0.28 ± 0.060.32 ± 0.02>50
α-NF0.12 ± 0.030.06 ± 0.010.51 ± 0.12