enzyme kinetics

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Optimization of Experimental Conditions of Automated Glucuronidation Assays in Human Liver Microsomes using a Cocktail Approach and Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry
Justine Badee, Nahong Qiu, Neil John Parrott, Abby C. Collier, Stephan Schmidt and Stephen Fowler

Drug Metabolism and Disposition November 26, 2018, dmd.118.084301; DOI: https://doi.org/10.1124/dmd.118.084301
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CHARACTERIZATION OF STEREOSELECTIVE METABOLISM, INHIBITORY EFFECT ON URIC ACID UPTAKE TRANSPORTERS, AND PHARMACOKINETICS OFLESINURAD ATROPISOMERS
Chun Yang, Dongmei Zhou, Zancong Shen, David M Wilson, Matthew Renner, Jeffrey N Miner, Jean-Luc Girardet and Caroline A Lee

Drug Metabolism and Disposition November 15, 2018, dmd.118.080549; DOI: https://doi.org/10.1124/dmd.118.080549
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Identification of 19-(S/R)Hydroxyeicosatetraenoic Acid as the First Endogenous Non-Competitive Inhibitor of Cytochrome P450 CYP1B1 with Enantioselective Activity
Sherif M. Shoieb, Ahmed A. El-Sherbeni and Ayman O.S. El-Kadi

Drug Metabolism and Disposition November 12, 2018, dmd.118.084657; DOI: https://doi.org/10.1124/dmd.118.084657

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