enzyme kinetics

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Content and activities of UGT2B7 in human liver in vitro and predicted in vivo: a bottom-up approach
Chen Xu, Jie Gao, Hai-Feng Zhang, Na Gao, Yuan-Yuan Guo, Yan Fang, Qiang Wen and Hai-Ling Qiao

Drug Metabolism and Disposition June 21, 2018, dmd.118.082024; DOI: https://doi.org/10.1124/dmd.118.082024
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Complete substrate inhibition of cytochrome P450 2C8 by AZD9496, an oral selective estrogen receptor degrader
Tashinga E Bapiro, Andy Sykes, Scott Martin, Michael Davies, James WT Yates, Matthias Hoch, Helen E Rollison and Barry Jones

Drug Metabolism and Disposition June 19, 2018, dmd.118.081539; DOI: https://doi.org/10.1124/dmd.118.081539
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CYP2D6 allelic variants *34, *17-2, *17-3, and *53 and a Thr309Ala mutant display altered kinetics and NADPH coupling in metabolism of bufuralol and dextromethorphan and altered susceptibility to inactivation by SCH 66712
Sarah M. Glass, Cydney M. Martell, Alexandria K. Oswalt, Victoria Osorio-Vasquez, Christi Cho, Michael J. Hicks, Jacqueline M. Mills, Rina Fujiwara, Michael J. Glista, Sharat S. Kamath and Laura Lowe Furge

Drug Metabolism and Disposition May 21, 2018, dmd.117.079871; DOI: https://doi.org/10.1124/dmd.117.079871

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