Research ArticlesIntestinal Drug Absorption and Metabolism III: Glycine Conjugation and Accumulation of Benzoic Acid in Rat Intestinal Tissue
REFERENCES (13)
- et al.
Biochem. Pharmacol.
(1963) - et al.
J. Pharm. Sci.
(1970) J. Biol. Chem.
(1951)- et al.
J. Chromatogr.
(1966) J. Pharm. Sci.
(1968)Int. Rev. Cytol.
(1968)
There are more references available in the full text version of this article.
Cited by (22)
Interest of metabonomic approach in environmental nephrotoxicants: Application to aristolochic acid exposure
2017, Food and Chemical ToxicologyCitation Excerpt :Given that mitochondria are the place for Krebs cycle and are quite abundant in the brush border of the proximal tubules, the deficiency in the Krebs cycle activity may be seen as a mitochondrial dysfunction. Hippurate is synthetized by the conjugation of glycine and benzoate in the kidney but also in the liver and in the intestine (Poon and Pang, 1995; Strahl and Barr, 1971). As previously shown by Deguchi et al. in 2005, circulating hippurate molecules are mostly uptaken by the organic anion transporter 1 in rats (rOat1) located in the basolateral membrane of kidney.
Conjugation and excretion of metabolites of 7-hydroxycoumarin in the small intestine of rats and guinea-pigs
1979, Biochemical PharmacologyA comparison of xenobiotic metabolism in cells isolated from rat liver and small intestinal mucosa
1979, Biochemical PharmacologyVaginal drug absorption in the rhesus monkey: Bioavailability method and assessment of estrogens
1979, International Journal of PharmaceuticsEverted rat intestinal sacs as an in vitro model for assessing absorptivity of new drugs
1977, Journal of Pharmaceutical SciencesThe metabolism of foreign compounds by the sheep gastrointestinal tract in vitro
1977, General Pharmacology
Copyright © 1971 Wiley-Liss, Inc., A Wiley Company. Published by Elsevier Inc. All rights reserved.