ArticlesSelf-Association and Solubility Behaviors of a Novel Anticancer Agent, Brequinar Sodium
References and Notes (49)
- et al.
J. Pharm. Sci.
(1970) - et al.
J. Pharm. Sci.
(1975) - et al.
J. Pharm. Sci.
(1973) J. Pharm. Sci.
(1979)- et al.
J. Pharm. Sci.
(1970) - et al.
J. Pharm. Sci.
(1978) - et al.
Int. J. Pharm.
(1984) - et al.
J. Pharm. Sci.
(1970) - et al.
J. Pharm. Sci.
(1975) - et al.
J. Pharm. Sci.
(1976)
J. Pharm. Sci.
J. Pharm. Sci.
J. Pharm. Sci.
J. Pharm. Sci.
J. Colloid Interface Sci.
J. Pharm. Sci.
J. Pharm. Sci.
J. Pharm. Sci.
J. Pharm. Sci.
J. Pharm. Sci.
J. Pharm. Sci.
Cancer Res.
Cancer Res.
Nature
Cited by (20)
Recent contributions of quinolines to antimalarial and anticancer drug discovery research
2021, European Journal of Medicinal ChemistryCitation Excerpt :In addition, despite its lower cLogP value, derivative 270a does not show a significantly increased water solubility compared to brequinar. Nevertheless, the promising results regarding the pharmacokinetic evaluation of derivative 270a legitimizes further investigation of 270a in the future [290]. Based on the zinc-binding properties of 8-hydroxyquinolines, Chen et al. designed a set of 8-hydroxyquinolines as matrix metalloproteinase (MMP) inhibitors, more specifically inhibitors of MMP-2 and MMP-9.
Amphiphilic drug–additive systems in aqueous and organic solvent–water mixed media: A comprehensive account on physicochemical properties
2020, Journal of Molecular LiquidsCitation Excerpt :The action and mode of aggregation of drugs from detailed studies can help to comprehend the physicochemical properties of drug/drug–additives systems. Various classes of amphiphilic drugs namely phenothiazine family drugs [53–56] and analgesics [57], benzodiazepine [44,58,59], tranquilizers [60], peptides [39,47,48] and nonpeptides [47,48,61], antibiotics [47,62], tricyclic antidepressants [46,63–65], antihistamines [66,67], anticholinergics [34,66], local anesthetics [68–70], non-steroidal anti-inflammatory [70,71] and anticancer drugs [72,73] have been explored to understand their physicochemical properties in aqueous medium. These investigations have been focused on several prospects which make the area quite vast.
Synergistic interaction between anti-allergic drug and cationic/anionic surfactants–Experimental and theoretical analysis
2020, Journal of Saudi Chemical SocietyCitation Excerpt :Some drugs are also self-associate and behave like a surfactant. Some example of amphiphilic drugs are antihistamines [6], anticholinergics [7], analgesic [8], phenothiazine [9–13], peptide [14], antibiotics, tricyclic antidepressant [15,16], β-blockers [17], local anesthetics [18,19], non-steroidal anti-inflammatory drugs [20] and anticancer drug [21]. The body of these drugs may be containing one aromatic nucleus or peptide nature.
Thermodynamic analysis of binding between drugs and glycosaminoglycans by isothermal titration calorimetry and fluorescence spectroscopy
2007, European Journal of Pharmaceutical SciencesSurface activity of a non-micelle forming compound containing a surface-active impurity
2007, International Journal of PharmaceuticsSelf-Association of Cromolyn Sodium in Aqueous Solution Characterized by Nuclear Magnetic Resonance Spectroscopy
2004, Journal of Pharmaceutical Sciences