Regular ArticleA New Cytochrome P450 Form Belonging to the CYP2D in Dog Liver Microsomes: Purification, cDNA Cloning, and Enzyme Characterization
References (0)
Cited by (56)
Electrochemistry of Canis familiaris cytochrome P450 2D15 with gold nanoparticles: An alternative to animal testing in drug discovery
2015, BioelectrochemistryCitation Excerpt :On the other hand, the enzyme immobilized in the presence of AuNps (GC/AuNPs/2D15) was capable of hydroxylating the metoprolol producing 30.7 ± 2.3 pmol of product at the higher metoprolol concentrations used. No O-desmethylated product was observed in line with previously published data on microsomal P450 2D15 [28]. Control experiments were also carried out in the absence of the protein and as expected no product was detected (data not shown).
Analysis of polymorphisms of canine Cytochrome P 450-CYP2D15
2020, Journal of Veterinary Pharmacology and TherapeuticsPersonalized medicine: going to the dogs?
2019, Human Genetics
Copyright © 1995 Academic Press. All rights reserved.