Regular ArticleP450-Catalyzed In-Chain Desaturation of Valproic Acid: Isoform Selectivity and Mechanism of Formation of Δ3-Valproic Acid Generated by Baculovirus- Expressed CYP3A1
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Present address: Molecular Biology Unit, Faculty of Pharmacy, University of Lisbon, Lisbon, Portugal.
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To whom correspondence should be addressed at Department of Medicinal Chemistry, University of Washington, Box 357610, Seattle, WA 98195. Fax: (206) 685-3252. E-mail:[email protected].