Regular ArticleIsolation and Characterization of the Human UGT2B7 Gene
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2003, British Journal of AnaesthesiaCitation Excerpt :Recently, it was shown that UGT2B7 is responsible for the glucuronidation of morphine and is capable of catalysing the glucuronidation of both the 3- and 6-hydroxyl moieties on these molecules.40 41 However, polymorphism in the coding sequence, as well as in the 5′-flanking region, may affect the rate of morphine glucuronidation and can result in individual differences.42 The SSS was developed as a measure of the severity of surgical stress.18
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These authors contributed equally.
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To whom correspondence should be addressed at Laboratory of Molecular Endocrinology, CHUL Research Center, 2705 Laurier Blvd., Québec, G1V 4G2, Canada. Fax: (418) 654-2761. E-mail: [email protected].