Regular ArticleFull-Length cDNA Cloning and Genomic Organization of the Mouse Liver-Specific Organic Anion Transporter-1 (lst-1)☆
References (29)
- et al.
Molecular characterization and tissue distribution of a new organic anion transporter subtype (oatp3) that transports thyroid hormones and taurocholate and comparison with oatp2
J. Biol. Chem.
(1998) - et al.
Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver
Gastroenterology
(1995) - et al.
Cloning and functional characterization of a novel rat organic anion transporter mediating basolateral uptake of methotrexate
J. Biol. Chem.
(1996) - et al.
Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1
J. Biol. Chem.
(1999) - et al.
Molecular characterization and functional regulation of a novel rat liver-specific organic anion transporter rlst-1
Gastroenterology
(1999) - et al.
A novel human hepatic organic anion transporting polypeptide (OATP2)
J. Biol. Chem.
(1999) - et al.
Molecular cloning of the gene for the human prostaglandin transporter hPGT: gene organization, promoter activity, and chromosomal localization
Biochem. Biophys. Res. Commun.
(1998) - et al.
Identification and functional characterization of the promoter region of the human organic anion transporting polypeptide gene
Hepatology
(1997) - et al.
Down-regulation by extracellular ATP of rat hepatocyte organic anion transport is mediated by serine phosphorylation of oatp1
J. Biol. Chem.
(2000) - et al.
Role of intracellular calcium and protein kinases in the activation of hepatic Na+/taurocholate cotransport by cyclic AMP
J. Biol. Chem.
(1993)
Akt-2 binds to Glut4-containing vesicles and phosphorylates their component proteins in response to insulin
J. Biol. Chem.
The secretory function of the liver: New aspects of hepatobiliary transport
J. Hepatol.
Expression cloning of a rat liver Na+-independent organic anion transporter
Proc. Natl. Acad. Sci. USA
Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain
Proc. Natl. Acad. Sci. USA
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Elucidation of OATP1B1 and 1B3 transporter function using transgenic rodent models and commonly known single nucleotide polymorphisms
2020, Toxicology and Applied PharmacologyCitation Excerpt :Choudhuri et al. (2000) reported the cloning of a new splice variant of rlst-1. Choudhuri et al. (2000) and Ogura et al. (2000) also cloned the rlst-1 and mlst-1 genes, respectively. The cloning of rlst-1 was also concurrently reported by Cattori et al. (2000), but it was named Oatp-4 for organic anion transporting polypeptide-4.
Organic anion transporting polypeptides in the hepatic uptake of PBDE congeners in mice
2011, Toxicology and Applied PharmacologyRegulation of Hepatobiliary Transporters during Liver Injury
2010, Comprehensive Toxicology, Second EditionExtra domains in secondary transport carriers and channel proteins
2006, Biochimica et Biophysica Acta - BiomembranesAlterations in transporter expression in liver, kidney, and duodenum after targeted disruption of the transcription factor HNF1α
2006, Biochemical PharmacologyCitation Excerpt :The Oatps, which are responsible for a large share of uptake of xenobiotics, have markedly decreased expression in these null mice. The most likely candidate for this poor uptake in the null mice may be Oatp1b2, which is the most similar in homology to the human Oatp-C and 8 [32]. This decreased uptake into liver may suggest that the dosage of glibenclamide should be carefully monitored in MODY-3 patients, otherwise increased serum levels could lead to hypoglycemia.
Liver
2004, Handbook of Stem Cells
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Sequence data from this article have been deposited in DDBJ/EMBL/GenBank data bases under the Accession Nos. AB031959 and AB037190 through AB037202.
- 1
Present address: Department of Drug Metabolism and Molecular Toxicology, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
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To whom correspondence should be addressed: Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, 3901 Rainbow Blvd., Kansas City, KS 66160-7417. Fax: (913) 588-7501. E-mail: [email protected].